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Truxima Approved as First Biosimilar to Non-Hodgkin's Lymphoma Drug

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READ MORE WEDNESDAY, Nov. 28, 2018 (HealthDay News) — Truxima ( rituximab -abbs) has been approved by the U.S. Food and Drug Administration as the first biosimilar to the non-Hodgkin’s lymphoma drug Rituxan , the agency said Wednesday. A biosimilar is a biological product that is approved based on data showing it is “highly similar” to a drug already approved by the FDA, with no “clinically meaningful differences in terms of safety, purity and potency,” the agency said in a news release. Truxima, as with Rituxan, is approved to treat adults with CD20-positive, B-cell non-Hodgkin’s lymphoma . The most common side effects of Truxima are infusion reactions, fever , low blood lymphocytes, chills , infection and weakness . The drug’s label includes a boxed warning that users also may be at increased risk of fatal infusion reactions, severe skin and mouth reactions, reactivation of hepatitis B , and a rare deadly brain infection known as PML. U...
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States Struggle With Onslaught of Opioid OD Deaths

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READ MORE By E.J. Mundell HealthDay Reporter THURSDAY, Aug. 30, 2018 (HealthDay News) — A new report on thousands of opioid overdose deaths across 11 states finds the problem is increasingly complex, but more can be done to stop it. The report, from the U.S. Centers for Disease Control and Prevention, looked at nearly 12,000 fatal opioid overdoses occurring between July 2016 and June 2017 in states across the Northeast, the Midwest and the West. “Most states were simultaneously struggling with a complex mix of prescription and illicit opioid deaths,” reported the team led by Christine Mattson, of the CDC’s National Center for Injury Prevention and Control. Her team found that, of the total fatal ODs, nearly six out of 10 (58.7 percent) involved illicit “street” drugs such as heroin or fentanyl . About 17 percent of the deaths involved prescription opioids such as Oxycontin , Vicodin and the like, while 18.5 percent involved a mix of prescription a...
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Darren Lehmann Reveals Emotional Struggles Post Ball-Tampering Scandal

READ MORE He tearfully quit in the aftermath despite being cleared of any direct role and contracted until the 2019 Ashes series in England, with Justin Langer taking over. His decision followed then captain Steve Smith, his deputy David Warner and opening batsman Cameron Bancroft receiving lengthy bans for the plot to alter the ball using sandpaper. “I saw people, and am still seeing people about it. That’s a work in progress,” Lehmann told the Sydney Daily Telegraph as he prepares to re-launch his career as a commentator. “I don’t think people know how much it affects people behind the scenes, but that’s one of those things that you go through. The help of family and close friends got me through.” Lehmann, who will be behind the microphone for Australia’s first one-day international against South Africa in Perth on Sunday, said the governing body offered psychological support “but you could always have more, can’t you?...
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